Clinical Trials
The fundamental goal of our work is to improve outcomes for the patients we serve. This makes the clinical translation of our therapies the most important step in the process. We collaborate with expert clinical trialists to develop clinical trials rooted in our preclinical work. The goal of these studies is to test these agents in a rigorous fashion and at the same time gain insight into the fundamental biology of the disease. SARC037 was the realization of this approach. This study was developed in collaboration with national experts in sarcoma. It has provided the basis for future clinical studies of trabectedin and analogs such as lurbinectedin. The LiFFT trial (Lurbinectedin in FET-Fused Tumors) is currently recruiting patients.